UPDATE: I think Serena is based on Leaf, and she is the heroine of the X/Y anime! I think she might be Blue/Leaf/Green because she is from Kanto and knew Ash (who is sadly based on Red) in their childhood.
And yeah... Agencyshipping is just pure awesome!
OK, this is getting ridiculous. I've been trying to not get owned by those two scenes in the manga for three months now, and it still hurts too much